How does cyanide inhibit superoxide reductase? Insight from synthetic FeIIIN4S model complexes
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چکیده
منابع مشابه
How does cyanide inhibit superoxide reductase? Insight from synthetic FeIIIN4S model complexes.
Superoxide reductases (SORs) are nonheme iron-containing enzymes that reduce HO(2) to H(2)O(2). Exogenous substrates such as N(3)(-) and CN(-) have been shown to bind to the catalytic iron site of SOR, and cyanide acts as an inhibitor. To understand how these exogenous ligands alter the physical and reactivity properties of the SOR iron site, acetate-, azide-, and cyanide-ligated synthetic mode...
متن کاملHow does cyanide inhibit superoxide reductase? Insight from synthetic FeN4S model complexes
and CN2 have been shown to bind to the catalytic iron site of SOR, and cyanide acts as an inhibitor. To understand how these exogenous ligands alter the physical and reactivity properties of the SOR iron site, acetate-, azide-, and cyanide-ligated synthetic models of SOR have been prepared. The x-ray crystal structures of azideligated [Fe(SN4(tren))(N3)] (3), dimeric cyanide-bridged ([Fe(SN4(tr...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2003
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.0637029100